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Is it Safe to Take Metformin and Trulicity Together?

diabetes medication

They say two is better than one—but is that really the case when it comes to medications? If you have diabetes, your doctor may have prescribed a combination of metformin and Trulicity to help keep your blood sugar levels in check. But is it safe to take these two medications together? Let’s find out!

What Are Metformin and Trulicity?

Metformin and Trulicity are two medications that have been approved by the Food and Drug Administration (FDA) for treating type 2 diabetes, a condition in which the body does not use insulin correctly. Metformin is an oral medication in tablet form that has been approved since the 1995. This medication works by lowering blood sugar levels by decreasing the amount of glucose produced by the liver and increasing the sensitivity of cells to insulin, allowing them to absorb more glucose from the bloodstream. It is usually taken once or twice a day with meals.

Free Blood Sugar Meter and Medication on the Blue Background Stock Photo

Trulicity is an injectable medicine that acts similarly to Metformin but can also help reduce appetite and promote weight loss, as well as improve blood sugar control. This medication works by stimulating production of insulin in response to high blood sugar levels, helping cells absorb excess glucose from the bloodstream. Trulicity is typically injected once a week before meals or at bedtime, depending on how it is prescribed. Both medications are used together with proper nutrition and exercise to help manage diabetes and reduce complications associated with poorly controlled blood sugar levels such as cardiovascular disease or kidney failure.

Are Metformin and Trulicity Safe Together?

The good news is yes—it’s generally safe to take metformin and Trulicity together. In fact, these two medications work synergistically, meaning they can be more effective when taken together but this can be consider under the right guidance of your medical practitioner. However, there are some potential side effects associated with taking both medications at once. These include nausea, vomiting, abdominal discomfort, headache and dizziness. Additionally, it’s important to make sure you are taking both medications as prescribed by your doctor in order to avoid any potential issues.

What Else Should I Consider When Taking Metformin and Trulicity Together?

It’s also important to note that while taking both medications together can be beneficial for some people with diabetes, it may not be suitable for everyone. For example, if you are pregnant or breastfeeding you should talk to your doctor before taking metformin or Trulicity. Additionally, it’s important to discuss any other medications or supplements you are currently taking with your doctor before starting a new treatment regimen such as this one.


Taking metformin and Trulicity together can be an effective way of managing type 2 diabetes symptoms—so long as you do so under proper medical supervision! As always when considering any changes in treatment plan for your diabetes management needs (or any other health concerns), make sure that you speak with your healthcare provider first about whether this combination of drugs is right for you.

With that said—we hope this post has given you more information on how these two drugs work together so that you can make an informed decision about what’s best for your health!

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