WHAT IS INDERAL?

Inderal (propranolol) belongs to a group of drugs called beta-blockers that block Beta-adrenergic receptors present in the heart, liver, pancreas, blood vessels, and the bronchial tree. This blockade of receptors can bring about changes in their function. The use of Inderal has been advised in conditions related to the heart and is limited for individuals experiencing asthma and diabetes.

Although not classified as an anxiolytic (antianxiety and antipanic), this drug is sometimes used “off label” as an anxiolytic to treat anxiety and panic. It is also prescribed, in some cases, to treat tremors and anxiety related to Parkinsonism, migraines, and various heart conditions such as arrhythmia and angina.

USES

Propranolol is used to treat high blood pressure, irregular heartbeats, shaking (tremors), and other conditions. It is used after a heart attack to improve the chance of survival. It is also used to prevent migraine headaches and chest pain (angina). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Preventing chest pain can help improve your ability to exercise.This drug works by blocking the action of certain natural chemicals in your body (such as epinephrine) that affect the heart and blood vessels. This effect reduces heart rate, blood pressure, and strain on the heart.

HOW DOES INDERAL WORK?

This medication acts on Beta-1 and Beta-2 receptors in the heart and the bronchial tree. Apart from this, Inderal’s inhibitory activity on the norepinephrine transporter (causing an increase in the release of norepinephrine in synapses) causes stimulation of Alpha-1 adrenoreceptors. This results in a decreased heart rate, which contributes to its anxiolytic effects.

WARNINGS

If you have asthma, very slow heartbeats, or a serious cardiac problem like “sick sinus syndrome” or “AV block,” you should not take Inderal (unless you have a pacemaker).

POSSIBLE SIDE EFFECTS

In case of serious side effects from this medication, a doctor should be consulted immediately. Serious side effects may include the following:

• Irregular heartbeat
• Breathlessness
• Chest pain
• Swollen hands or feet
• Bleeding
• Weight gain

STORAGE

stored at room temperature, 15 to 30 C (59 to 86 F).

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