WHAT IS BONVIVA?

Bonviva is a medicine that contains the active substance ibandronic acid. It is available as tablets (150 mg) and as a solution for injection in a prefilled syringe (3 mg).

Bonviva is used to treat osteoporosis (a disease that makes bones fragile) in women who have been through the menopause and are at risk of developing bone fractures (breaks). Its effect in reducing the risk of spine fractures has been shown in studies, but its effect on the risk of fractures of the neck of the femur (the top of the thighbone) has not been established. The medicine can only be obtained with a prescription.

USE 

Bonviva is used to treat osteoporosis (a disease that makes bones fragile) in women who have been through the menopause and are at risk of developing bone fractures (breaks).

HOW TO USE BONVIVA TABLET

Take this medication at the dose and for the duration prescribed by your doctor. Take it all at once. It should not be chewed, crushed, or broken. BONVIVA 150 MG TABLET should be taken on an empty stomach.

STORAGE

Store below 30°C.

BENEFITS OF BONVIVA TABLET

In Osteoporosis:
Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause or who are taking steroids. This condition can be treated with bone-strengthening medicines. BONVIVA 150 MG TABLET slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. You can also help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D, and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.

HOW DOES BONVIVA WORK?

Osteoporosis happens when not enough new bone grows to replace the bone that is naturally broken down. Gradually, the bones become thin and fragile, and more likely to break. Osteoporosis is more common in women after the menopause, when the levels of the female hormone oestrogen fall, since oestrogen helps to keep bones healthy.

The active substance in Bonviva, ibandronic acid, is a bisphosphonate. It stops the action of the osteoclasts, the cells that are involved in breaking down the bone tissue. Blocking the action of these cells leads to less bone loss.

WHAT IS THE RISK ASSOCIATED WITH BONVIVA?

The most common side effects with Bonviva (seen in between 1 and 10 patients in 100) are arthralgia (joint pain) and influenza (flu)-like symptoms. The most serious side effects with Bonviva are anaphylactic reaction (severe allergic reaction), atypical fractures of the femur (an unusual type of fracture of the bone of the upper leg), osteonecrosis of the jaw (damage to the bones of the jaw, which could lead to pain, sores in the mouth or loosening of teeth), gastrointestinal (stomach and gut) irritation and eye inflammation. For the full list of all side effects reported with Bonviva, see the package leaflet.

Bonviva must not be used in patients who have hypocalcaemia (low blood calcium levels). The tablets must not be used in patients who have abnormalities of the oesophagus or who cannot stand or sit upright for at least an hour. For the full list of restrictions with Bonviva, see the package leaflet.

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