WHAT IS BRINZOLAMIDE?

Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase inhibitor. Carbonic anhydrase (CA) is an enzyme found in many tissues of the body including the eye. In humans, carbonic anhydrase exists as a number of isoenzymes, the most active being carbonic anhydrase II (CA-II). Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion, presumably by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. The result is a reduction in intraocular pressure. Brinzolamide is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.

USES

Brinzolamide is used to treat high pressure inside the eye due to glaucoma (open angle-type) or other eye diseases (e.g., ocular hypertension). Lowering high pressure inside the eye helps to prevent blindness. This medication works by decreasing the amount of fluid within the eye. It belongs to a class of drugs known as carbonic anhydrase inhibitors. Brinzolamide can decrease intraocular pressure by approximately 16-19% in patients with elevated intraocular pressure.

HOW SHOULD I USE BRINZOLAMIDE?

1.Wash your hands well before you use the drops.
2. Remove the cap.
3. Tilt your head back a little and pull the lower lid of your eye out to form a pocket.
4. Hold the bottle upside down near to your eye. …
5. Apply enough pressure to the base of the bottle to release one drop into your eye.

BRINZOLAMIDE OPHTHALMIC SIDE EFFECTS

These common side effects happen in more than 1 in 100 people. Keep using the medicine, but talk to your doctor or pharmacist if these side effects bother you or do not go away:

• an itchy or painful eye and a feeling that something’s in your eye, blurred vision, or watery eyes.
• your eyes become sensitive to bright light (photophobia).
• a bad or unusual taste in your mouth

STORAGE

Store between 39-86 degrees F (4-30 degrees C) away from light and moisture.Do not store in the bathroom.

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