INTRODUCTION
One (1) mL contains insulin lispro (recombinant DNA origin produced in Escherichia coli) 100 U (equivalent to 3.5 mg). Each vial includes 10 mL equivalent to insulin lispro 1,000 U.
Humalog also contains the following inactive ingredients: m-cresol (3.15 mg/mL), glycerol, dibasic sodium phosphate?7H2O, zinc oxide and water for injection. Hydrochloric acid and sodium hydroxide may be used to adjust the pH to 7-7.8.
USE
Humalog Mix25 KwikPen is used to treat diabetes. It is a premixed suspension. Its active substance is insulin lispro. 25 % of the insulin lispro in Humalog Mix25 KwikPen is dissolved in water and it works more quickly than normal human insulin because the insulin molecule has been changed slightly. 75 % of the insulin lispro in Humalog Mix25 KwikPen is available in a suspension together with protamine sulphate, so that its action is prolonged. You get diabetes if your pancreas does not make enough insulin to control the level of glucose in your blood.
Humalog Mix25 is a substitute for your own insulin and is used to control glucose in the long term. Humalog Mix25 works very quickly and longer than soluble insulin. You should normally use Humalog Mix25 within 15 minutes of a meal.
CONTRAINDICATIONS
Hypersensitivity to insulin lispro or any of the excipients of Humalog. Hypoglycemia.
PRECAUTIONS
Transferring from other types of insulin. Renal & hepatic impairment. Presence of illness or emotional disturbances. Patients who undertake increased physical activity or change in the usual diet. Concomitant use w/ pioglitazone. May impair ability to drive or operate machinery. Pregnancy & lactation.
STORAGE
Store all unopened insulin containers in the refrigerator between 36-46 degrees F (2-8 degrees C). Do not freeze, and do not use insulin that has been frozen. Store in the carton to protect from light. Do not refrigerate pens that are currently in use. Discard pens in use after 10 days, even if there is insulin left. Do not store in the bathroom. Keep all medicines away from children and pets.
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