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Vytorin (Ezetimibe/Simvastatin) used along with a proper diet to help lower “bad” cholesterol and fats (such as LDL, triglycerides) and raise “good” cholesterol (HDL) in the blood. Ezetimibe works by reducing the amount of cholesterol your body absorbs from your diet. Simvastatin belongs to a group of drugs known as “statins.” It works by reducing the amount of cholesterol made by the liver. In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details. Lowering “bad” cholesterol and triglycerides and raising “good” cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks. The simvastatin component of Vytorin belongs to a class of drugs called HMG-CoA reductase inhibitors, commonly called “statins.” Statins reduce cholesterol by blocking an enzyme in the liver (HMG-CoA reductase) that produces cholesterol. Statins lower total and LDL cholesterol in the blood as well as triglycerides. They also increase HDL cholesterol. LDL cholesterol is believed to be an important cause of coronary artery disease. Lowering LDL cholesterol levels slows and may even reverse coronary artery disease. Raising HDL cholesterol levels also may slow coronary artery disease. The FDA approved Vytorin in July 2004.
Vytorin (Ezetimibe/Simvastatin) comes as a tablet that’s taken by mouth. The active drugs in Vytorin are ezetimibe and simvastatin. Vytorin tablets are available in four strengths, which are given in milligrams (mg):
Tell your doctor if: you are pregnant or intend to become pregnant. Vytorin (Ezetimibe/Simvastatin) should not be used during pregnancy, you are breast-feeding. Vytorin should not be used while breast feeding, you have unexplained muscle pain, tenderness or weakness not caused by exercise. This is because on rare occasions, muscle problems can be serious, including muscle breakdown resulting in kidney damage that can lead to death. Your doctor may do a blood test to check for certain muscle problems, you are taking niacin or a niacin-containing product, you have, or have had, any medical conditions, including liver disease or liver problems, your doctor will do a blood test to make sure you have no problems with your liver, you have kidney disease, diabetes or any other medical problems, you drink alcohol regularly, you have any allergies to any other medicines or any other substances, such as foods, preservatives or dyes. If you have not told your doctor about any of the above, tell them before you take any Vytorin.
Take Vytorin (Ezetimibe/Simvastatin) only when prescribed by your doctor. The recommended dose in adults (18 years and over) is one Vytorin (Ezetimibe/Simvastatin) 10/10, 10/20, 10/40 or 10/80 tablet once a day, in the evening. Your doctor will adjust your Vytorin (Ezetimibe/Simvastatin) dose depending on your response. The recommended dose in adolescents (10 to 17 years of age) with familial hypercholesterolaemia is one Vytorin (Ezetimibe/Simvastatin) 10/10, 10/20 or 10/40 tablet once a day, in the evening. The maximum recommended dose in adolescents is 10/40 mg. Because of the increased risk of muscle problems, the Vytorin (Ezetimibe/Simvastatin) 10/80 tablet is only for patients at high risk of heart disease problems who have not yet reached their cholesterol goal on lower doses. Swallow Vytorin (Ezetimibe/Simvastatin) with a glass of water. Follow all directions given to you by your doctor and pharmacist carefully. They may differ from the information contained in this leaflet. If you do not understand the instructions, ask your doctor or pharmacist for help. When to take it. Vytorin (Ezetimibe/Simvastatin) should be taken once a day, in the evening. The liver produces its greatest amount of cholesterol when the body is at rest and when there is no dietary intake. For most people this is at night when asleep. Therefore, Vytorin (Ezetimibe/Simvastatin) is more effective when taken in the evening. A good time would be after your evening meal. However, it does not matter whether you take it before or after food.
The most common side effects of Vytorin (Ezetimibe/Simvastatin) are: headache, nausea, vomiting, diarrhea, muscle pain, and abnormal liver tests. Hypersensitivity reactions also have been reported. The most serious potential side effects are liver damage and muscle inflammation or breakdown. The simvastatin component of Vytorin is a statin. Therefore, it shares side effects, such as liver and muscle damage associated with statins. Serious liver damage caused by statins is rare. More often, statins cause abnormalities of liver tests, and, therefore, periodic measurement of liver tests in the blood is recommended for all statins. Abnormal tests usually return to normal even if a statin is continued, but if the abnormal test value is greater than three times the upper limit of normal, the statin usually is stopped. Liver tests should be measured before Vytorin is started and periodically thereafter or if there is a medical concern about liver damage.
Can Vytorin (ezetimibe / simvastatin) cause liver damage?
Vytorin (ezetimibe / simvastatin) can cause liver damage. You should not take Vytorin (ezetimibe / simvastatin) if you have active liver disease. Your provider may want to check your liver function with a blood test before starting the medication and regularly thereafter. Call your provider if you experience loss of appetite, stomach pain, dark urine, yellowing of the skin or eyes, and/or tiredness and weakness.
Vytorin (ezetimibe / simvastatin) lowers “bad” cholesterol (LDL) by decreasing the amount your body makes. Since your body naturally makes the most cholesterol at night, Vytorin (ezetimibe / simvastatin) works best when taken in the evening.
Vytorin is a combination of ezetimibe (Zetia) and simvastatin (Zocor) that is used for treating high levels of cholesterol in the blood. Vytorin reduces total cholesterol and low-density lipoprotein (LDL or “bad”) cholesterol while it increases high density lipoprotein (HDL or “good”) cholesterol. The ezetimibe component of Vytorin lowers blood cholesterol by blocking the absorption of cholesterol, including dietary cholesterol, from the intestine. It does not affect the absorption of triglycerides. Buy online at www.usascripthelpers.com. USAScriptHelpers is committed to provide Americans safe, approved and affordable medications. USH not only offers human medications but also PetMeds. USAScriptHelpers has over 10+ years of experience when it comes to handling your prescription and over-the-counter needs.
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USA Script Helpers only contracts reputable dispensing vendors.