Diabetes mellitus (DM) is a common condition encountered in both dogs and cats. In many cases it can be managed well, but there are cases that are problematic initially, or which become unstable. In newly diagnosed cats and dogs, insulin glargine is the insulin of choice. Glargine is a long-acting basal insulin. Used in conjunction with high-protein, low-carbohydrate diets. Diabetes mellitus is a common endocrine disease in dogs and cats. Diabetes mellitus is a chronic disorder of carbohydrate metabolism due to relative or absolute insulin deficiency. Most cases of spontaneous diabetes occur in middle-aged dogs and middle-aged to older cats. In dogs, females are affected twice as often as males, and incidence appears to be increased in certain small breeds such as Miniature Poodles, Dachshunds, Schnauzers, Cairn Terriers, and Beagles, but any breed can be affected. Obese male cats seem to be more commonly affected than female cats, and breeds such as Burmese, Russian Blue, Norwegian Forest Cat, Abyssinian, and Tonkinese appear predisposed.

Lantus or Insulin Glargine is a longer-acting insulin commonly in cats because it has an adequate duration of action in most diabetic cats. Several studies have demonstrated that glargine is effective for controlling blood sugar levels in diabetic cats and achieving high remission rates. Lantus can also be used in dogs. It is a human analog insulin with modifications that provide variable solubility at different pHs.

How Does Lantus Work?

Lantus is a synthetic or analog insulin manufactured by Sanofi-Aventis. Like other kinds of injectable insulin, it provides the body with the hormones necessary to help lower the amount of glucose in the bloodstream. Lantus releases insulin slowly in the body, which helps minimize the number of injections required to maintain healthy glucose levels. Its long-lasting effects have helped make it an increasingly preferred method for managing feline diabetes, since cats metabolize insulin around twice as fast as people. Lantus typically remains active in cats for around 12 hours per dose, which may require owners to administer the medicine twice a day. Owners should always consult with a veterinarian regarding specific dosage recommendations and instructions. Although the product is not FDA-approved for feline use, it may be available by prescription from a veterinarian. Unlike some older insulin products, the active ingredient in Lantus, glargine insulin, is not derived from animal-based materials. The clear liquid medication is often prescribed in 10 mL vials intended for use with syringes. Lantus is also available in 3 mL doses contained inside insulin pen cartridges. These reusable devices feature disposable needles and are sometimes favored for their size and convenience.

What Are The Possible Side Effects?

The most common side effect is hypoglycemia (low blood sugar). Symptoms include the following: weakness, shaking or trembling, head tilting, drowsiness, and inability to coordinate muscle activity. Left untreated, it can progress to seizures, blindness, bizarre behavior and coma. Other side effects include restlessness, hunger and muscle twitching. If you notice anything unusual, contact your veterinarian.

What You Should Know

Precautions: Urinary-tract infections are a common secondary problem in cats with diabetes. Intact female cats should be neutered because the increased progesterone with diestrus makes the management of diabetes more difficult. Dietary changes can affect insulin requirements. Insulin may be used in pregnant animals, although breeding animals with diabetes is generally discouraged. Insulin may be used in lactating animals. Injection-site reactions may occur. It is important to use multiple sites.

Insulin therapy is still the primary therapy for all diabetic dogs and cats. Several insulin options are available for each species, including veterinary registered products and human insulin preparations. The insulin chosen depends on the individual patient’s requirements. Intermediate-acting insulin is usually the first choice for dogs, and longer-acting insulin is the first choice for cats. Once the insulin type is chosen, the best method of insulin administration should be considered. With this, Lantus Insulin (insulin glargine injection) is one of the pet insulin medications in demand. This an injectable, long-acting insulin for treating diabetes mellitus in dogs and cats. Lantus Insulin controls blood glucose levels to help alleviate the symptoms of diabetes. It is used with U-100 insulin syringes only (sold separately). Lantus Insulin requires a prescription from your veterinarian.

Lantus contains the drug insulin glargine, which is classified as a long-acting insulin.  Lantus is given as an injection just under your skin (a subcutaneous injection). The drug comes as a solution inside 10-milliliter (mL) vials that hold 100 units of insulin glargine per ml. The vial is used with needles, which aren’t included with the vial.  Lantus also comes as a prefilled Solostar pen. Each pen contains 3 mL of drug solution that has 100 units of insulin per mL of solution.

Lantus is used to improve blood sugar control in adults and children with diabetes mellitus. It is for use in adults with type 1 or type 2 diabetes, and in children at least 6 years old with type 1 diabetes. Some brands of insulin glargine are for use only in adults. Carefully follow all instructions for the brand of insulin glargine you are using.


Follow all package directions for proper use/injection/storage of the particular type of device/insulin you are using. Your health care professional will teach you how to properly inject this medication. If any of the information is unclear, consult your doctor or pharmacist.

Do not inject cold insulin because this can be painful. The insulin container you are currently using can be kept at room temperature (see also Storage section). Wash your hands before measuring and injecting insulin. Before using, check the product visually for particles, thickening, or clumps. If any are present, discard that container. Insulin glargine should be clear and colorless. To avoid damaging the insulin, do not shake the container.

The dosage is based on your medical condition and response to treatment. Measure each dose carefully, and use exactly as prescribed by your doctor. Even small changes in the amount of insulin may have a large effect on your blood sugar. If you are using the cartridge form of this insulin and a special injecting device with a digital display, take care to read the display right-side up. If you read the display upside-down, you may inject the wrong amount of insulin. Ask your pharmacist if you are unsure how to properly use this type of injecting device.

Before injecting each dose, make sure the injection site is clean and dry. Inject this medication under the skin of the abdomen, upper arms, or thighs, usually once daily or as directed by your doctor. Do not rub the injection site. Do not inject into a vein or muscle. Change where you inject each time to lessen the risk of problems or damage under the skin (for example, pits/lumps or thickened skin). Do not inject into skin that is red, swollen, itchy, or damaged.

Use this medication regularly as directed by your doctor in order to get the most benefit from it. You may inject insulin glargine once daily at any time during the day (such as before breakfast or at bedtime) but you should inject at the same time each day. Carefully follow the insulin treatment plan, meal plan, and exercise program your doctor has recommended.

Do not mix this product with other insulins or solutions, or use it in an insulin pump.

Do not change brands or types of insulin without directions on how to do so from your doctor.

Monitor your blood sugar on a regular basis. Keep track of the results, and share them with your doctor. This is very important in order to determine the correct insulin dose.

If you are measuring doses from vials, do not reuse needles and syringes. If you are using the cartridges or pens, use a new needle each time. Do not share your pen device with another person, even if the needle is changed. You may give other people a serious infection, or get a serious infection from them. Learn how to store and discard medical supplies safely.

Tell your doctor if your condition does not improve or if it worsens (your blood sugar is too high or too low).


Lantus can cause mild or serious side effects. The following lists contain some of the key side effects that may occur while taking Lantus. These lists don’t include all possible side effects.


The more common side effects* of Lantus can include:

  • injection site reactions (redness, itchiness, pain, or tenderness around the injection area)
  • lipodystrophy (changes in skin thickness near the injection site)
  • itchy skin
  • rash
  • edema (swelling), typically in your legs, ankles, or feet
  • weight gain
  • upper respiratory infections, such as the common cold
  • hypoglycemia(low blood sugar levels)

Most of these side effects may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk with your doctor or a pharmacist from our contracted pharmacy department.


Serious side effects from Lantus aren’t common, but they can occur. Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency.

  • Serious side effects and their symptoms can include the following:
  • Hypokalemia (low potassium levels). Symptoms can include:
  • weakness
  • fatigue (lack of energy)
  • muscle cramping
  • abnormal heart rhythm (a heartbeat that’s too fast, too slow, or uneven)
  • paralysis (loss of movement in a body part)
  •  respiratory failure (meaning your lungs can’t release oxygen into your blood)
  • Severe hypoglycemia (very low blood sugar levels).
  • Allergic reaction.
  • Never share a LANTUS Solostar prefilled pen between patients, even if the needle is changed. (5.1)
  • Hyperglycemia or hypoglycemia with changes in insulin regimen: Make changes to a patient’s insulin regimen (e.g., insulin strength, manufacturer, type, injection site or method of administration) under close medical supervision with increased frequency of blood glucose monitoring.
  • Hypoglycemia: May be life-threatening. Increase frequency of glucose monitoring with changes to: insulin dosage, coadministered glucose lowering medications, meal pattern, physical activity; and in patients with renal or hepatic impairment and hypoglycemia unawareness.
  • Medication Errors: Accidental mix-ups between insulin products can occur. Instruct patients to check insulin labels before injection.
  • Hypersensitivity reactions: Severe, life-threatening, generalized allergy, including anaphylaxis, can occur. Discontinue LANTUS. Monitor and treat if indicated.
  • Hypokalemia: May be life-threatening. Monitor potassium levels in patients at risk of hypokalemia and treat if indicated.
  • Fluid retention and heart failure with concomitant use of thiazolidinediones (TZDs): Observe signs and symptoms of heart failure; consider dosage reduction or discontinuation of TZD if heart failure occurs.

USA Script Helpers is an established Pharmacy Partner with over 10 years of experience in the online pharmaceutical industry. In conjunction with its contracted* licensed Pharmacy department, USA Script Helpers refers its customers to its’ contracted* Pharmacy department to ensure that Americans all across the USA have access to the medications they need. Whether it be tablet medications, topical creams, patches, various insulins including (Lantus SoloStar Pens, Lantus Vials, Lantus Cartridges, Humalog, Novolog etc.).

USA Script Helpers not only retails human medications but also pet medications. USH offers a variety of medications including both brand name and generic equivalent. USA Script Helpers is committed to providing safe medications that you can truly rely on. USA Script Helpers is open 365 days a year to ensure that customers have access to the customer support that they need. Call us today at 1 (888) 646-7749 or simply place your order online. When Medicare is out, count us in.