Skyrizi is a medication that has recently been approved last 2022 by the FDA for the treatment of Crohn’s disease, rheumatoid arthritis, and multiple sclerosis. Skyrizi is an immunomodulator, which means that it helps to modulate the immune system.
In the case of Crohn’s disease, Skyrizi helps to reduce inflammation in the digestive tract. For rheumatoid arthritis, Skyrizi helps to reduce inflammation in the joints. And for multiple sclerosis, Skyrizi helps to reduce inflammation in the central nervous system.
How Skyrizi Works
Skyrizi offers safe and effective relief from many of the common symptoms associated with these conditions while being well tolerated by most patients. Patients typically receive two doses four weeks apart when they begin the treatment. Subsequent doses are then given every 12 weeks thereafter to achieve maximum results.
Skyrizi works by binding to a protein called interleukin-23 (IL-23). IL-23 is a cytokine, which is a type of protein that helps to regulate the immune system. By binding to IL-23, Skyrizi prevents it from binding to its receptor. This leads to a reduction in inflammation.
Skyrizi is given as an injection under the skin. The injections are given every 8 weeks. The most common side effects of Skyrizi include injection site reactions, upper respiratory tract infections, headache, and fatigue.
Who Can Take Skyrizi?
Skyrizi is approved for use in adults with Crohn’s disease who have not responded well to other medications. It is also approved for use in adults with active rheumatoid arthritis who have not responded well to other medications. And it is approved for use in adults with relapsing forms of multiple sclerosis.
Common Side Effect of Skyrizi
Adverse effects reported by people taking Skyrizi include upper respiratory infections, headaches and other common cold type symptoms; more serious side effects are possible but rare.
People using this drug should contact their doctor right away if they experience signs such as chest pain or shortness of breath; itching or hives; swelling around the eyes or tongue; severe muscle pain; yellowing skin or eyes; fever; confusion or extreme fatigue; or a sore throat accompanied by a fever.
Skyrizi is an innovative new treatment option for those living with moderate to severe plaque psoriasis, active psoriatic arthritis or moderately-to-severely active Crohn’s disease. If you have any of these conditions and are looking for an effective treatment option then talk to your doctor about if Skyrizi may be right for you.
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