USA Script Helpers

Attention All Customers Effective as of Thursday, October 5th 2023 8PM CST *ALL orders for Ozempic 4mg/3ml will be temporarily unavailable for purchase until Mid November. Join our waiting list or contact us directly to be notified once inventory is available. Ozempic 2mg/3ml is still available for purchase. Maximum 3 pens per customer. We sincerely thank you for your cooperation.

⚠️January 2nd • Cold Chain Shipments will resume.
USA Script Helpers

Use USH5OFF code to receive 5% off on your first order. Call Us Now : 1 (888) 646-7749

Use USH5OFF code to receive 5% off on your first order. Call Us Now : 1 (888) 646-7749

What Are The Most Common Side Effects Of Ursodiol?

fatty liver

Ursodiol is an FDA-approved medication used to treat conditions like gallstones and nonalcoholic fatty liver disease. While it is generally safe and effective, there are some common side effects that you should be aware of. In this article, we will look at what the most common side effects of ursodiol are and how they can be managed. Keep reading to learn more about this important information.

Overview Of Ursodiol

Ursodiol is a bile acid prescribed to treat certain liver and gallbladder conditions. It works by decreasing the production of cholesterol in the body and helps break down cholesterol that has already been deposited in the gallbladder. Ursodiol is available as an oral capsule, tablet, or liquid solution.

It is important to tell your doctor if you are under any medication before starting ursodiol as it may interact with other medications. It is also important to inform your doctor if you have any allergies or medical conditions so they can assess whether this medication is right for you.

Possible Side Effects of Ursodiol

The most common side effects of ursodiol are nausea, vomiting, and abdominal cramping. Less common side effects may include diarrhea, headache, fever, back pain, dizziness, rash or hives. Rarely reported but serious side effects can include liver toxicity and allergic reactions.

Be sure to talk to your doctor about any other medications or supplements  that could interact with ursodiol. Your doctor may suggest other treatments if necessary to help reduce the risk of potential side effects.

Gastrointestinal Issues

One of the most common side effects associated with Ursodiol is gastrointestinal issues. In this article, we will explore these gastrointestinal side effects, their potential causes, and provide tips on managing them effectively.

  • Nausea: Nausea is a common side effect reported by individuals. It is characterized by a feeling of queasiness or an urge to vomit. If you experience nausea , try  the medication with food to help minimize this side effect. Eating smaller, more frequent meals throughout the day can also be beneficial. Additionally, avoid consuming greasy or spicy foods that may exacerbate nausea.
  • Upset Stomach: Some individuals may experience an upset stomach, which can manifest as discomfort, bloating, or a general feeling of unease in the abdominal region. To alleviate an upset stomach, consider eating smaller portions and avoiding foods that are known to trigger gastrointestinal discomfort, such as fatty or fried foods. Opt for easily digestible foods like plain rice, boiled potatoes, or light soups. Drinking plenty of water and avoiding carbonated drinks can also help soothe the stomach.

Illustration of liver on woman's body against gray background, Hepatitis, Concept with Healthcare And Medicine Illustration of liver on woman's body against gray background, Hepatitis, Concept with Healthcare And Medicine fatty liver stock pictures, royalty-free photos & images

  • Diarrhea: Diarrhea is another gastrointestinal side effect that can occur. It is characterized by loose, watery stools and increased bowel movements. If you experience diarrhea, it is important to stay hydrated by drinking plenty of fluids to prevent dehydration. Avoiding foods that can aggravate diarrhea, such as spicy or fatty foods, dairy products, and caffeine, may also be beneficial. If diarrhea persists or becomes severe, consult your healthcare provider.
  • Abdominal Pain: Some individuals may experience abdominal pain or discomfort . This pain can range from mild to severe and may be accompanied by bloating or cramping sensations. If you experience abdominal pain, try applying a heating pad or use over-the-counter pain relievers, as recommended by your healthcare provider. However, it is important to consult your healthcare provider if the pain persists or worsens.
  • Indigestion: Indigestion, also known as dyspepsia, is characterized by a feeling of fullness or discomfort in the upper abdomen, often accompanied by bloating, belching, or heartburn. To alleviate indigestion, consider eating smaller meals and avoiding foods that are known to trigger indigestion symptoms, such as fatty or spicy foods, citrus fruits, and carbonated drinks. It may also be helpful to avoid lying down immediately after eating and to maintain an upright posture to aid digestion.

It is important to note that these gastrointestinal side effects are usually temporary and may subside as your body adjusts to the medication. However, if these side effects persist, worsen, or become concerning, it is important to consult your healthcare provider for further evaluation and guidance.

Skin-Related Reactions

Turning to the side effects associated with ursodiol, skin-related reactions are among the most common. These include itching, rashes, and hives. In some cases, these reactions can be severe enough that they require medical attention. It’s important to report any such reaction to your doctor right away.

It is also possible for it to cause more serious skin-related reactions such as Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN). Symptoms of these conditions include extreme rash, blisters, fever, and intense itching. If you experience any of these symptoms, contact your healthcare provider immediately.

In addition to the above mentioned skin-related reactions, it can cause changes in the color of your skin. This is usually a yellowish discoloration in areas exposed to sunlight or artificial light. While this side effect isn’t dangerous, it may be distressing and should still be reported to your doctor for further evaluation.

Other Potential Adverse Reactions

The most common side effects of ursodiol include nausea, headaches, and abdominal pain. In rare cases, more serious adverse reactions have been reported. These include severe allergic reactions such as hives or difficulty breathing, changes in liver enzyme levels, and kidney problems. It is also possible for it to interact with other medications, resulting in an increased risk of side effects.

It is important to tell your doctor if any side effects occur while under this medication. This includes any new symptoms that may develop during treatment or if existing symptoms become worse. Your doctor can adjust the dosage accordingly or provide alternative treatments if necessary. They can also recommend lifestyle modifications to reduce the risk of side effects occurring.

When To Seek Medical Attention

If any of these side effects become severe or persistent, it is important to seek medical attention right away. If you experience any of the following symptoms while taking ursodiol, contact your doctor immediately: difficulty breathing; swelling of the face, tongue, lips or throat; dark urine; abdominal pain; yellowing of the skin or eyes; fever; confusion; extreme fatigue; or unusual bleeding/bruising. Additionally, if you have been using it for a prolonged period and have not seen any improvement in your condition after 3 months then you should consult your doctor about other treatment options.

Seeking medical advice promptly is always recommended in order to avoid any further complications from occurring due to taking ursodiol. It is also important to keep track of any changes in symptoms during treatment so that they can be discussed with a doctor if necessary. Early detection and prompt treatment can help ensure that the best outcome is achieved when using this medication.


In conclusion, ursodiol is a medication used to treat certain liver and gallbladder conditions. While it can be effective in treating these conditions, it may also cause some side effects in some users.  It’s important to speak with a healthcare provider if you experience severe or persistent side effects while taking ursodiol. They can help you determine the best course of action for managing your symptoms and minimizing any potential risks associated with the medication.

Leave a Replay

Canadian Pharmacy
At USA Script Helpers we believe safe, accessible health care should be available to everyone and everywhere.

Contact Details

Recent Posts


The holiday season commences on November 15th, 2023, and concludes on January 15th, 2024. Please be aware that shipping times are slower during the holiday season. Canada Post also suspends their shipping guarantee during this period. We kindly ask that you place your orders as early as possible to avoid the holiday rush.


All products sourced from Canada may take up to 10-14 business days to be received from the original shipment date. Additionally, internationally sourced products could take anywhere from 6 to 8 weeks to reach your doorstep from the shipping date. We appreciate your choice in USA Script Helpers.

USA Script Helpers


If you have any questions or would like to speak to a Pharmacist from our contracted Pharmacy department, please do not hesitate to give us a call at our toll free number: 1 (888) 646-7749.

3-Month Supplies

As the amount of medicine constituting a day supply depends on your doctors directions for use, different patients are permitted to order different quantities. Placing an order for more than a 3-month supply may delay your order as we will need to contact you. Contact us for assistance if your 3-month rule compliant desired quantity is not shown.